Caragata EP, Rances E, Hedges LM, Gofton AW, Johnson KN, O'Neill SL, McGraw EA

Dietary cholesterol modulates pathogen blocking by Wolbachia

PLoS Pathogens 9(6): e 1003459. doi:10.1371/journal.ppat.1003459

Wolbachia pipientis protects its hosts from a range of pathogens by limiting their ability to form infections inside the insect. This paper examines the involvement of cholesterol in pathogen blocking using a system of dietary manipulation in Drosophila melanogaster in combination with challenge by Drosophila C virus (DCV), a common fly pathogen.

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